Main Street Chillicothe

Chillicothe is a thriving community in north central Missouri, and our historic Main Street is the heart of this great town. Learn why this charming community is the greatest thing since ... well, you know.

Support Main Street

With support, we can bring new energy to the downtown and benefit the community in many different ways.

What's Happening?

October 31st 2019
Boofest

November 30th, 2019
Small Business Saturday

What's new?

What a whirlwind of a quarter! This time of year is filled with such color and vibrancy downtown, and it's always amazing to see the crowds of people enjoying all of the different businesses ...Read More
Main Street wishes to welcome Wendy Wilson owner of The Charmed Nook as a new business to downtown. The Charmed Nook opened in April 2019. Wendy and husband Michael Wilson live in Chillico ...Read More
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2019 © Main Street Chillicothe  |  (660) 646-4071  |  514 Washington Street  |  Chillicothe, MO 64601