Main Street Chillicothe

Chillicothe is a thriving community in north central Missouri, and our historic Main Street is the heart of this great town. Learn why this charming community is the greatest thing since ... well, you know.

Support Main Street

With support, we can bring new energy to the downtown and benefit the community in many different ways.

What's Happening?

August 1, 2015
Sliced Bread Saturday

What's new?

Join us on May 27 for our annual luncheon as we celebrate the accomplishments of the past year and recognize those people that have made considerable contributions to our organization and to ...Read More
Main Street Chillicothe has been designated as an accredited National Main Street Program for meeting the commercial district revitalization performance standards set by the National Main St ...Read More
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2014 © Main Street Chillicothe  |  (660) 646-4071  |  514 Washington Street  |  Chillicothe, MO 64601