Main Street Chillicothe

Chillicothe is a thriving community in north central Missouri, and our historic Main Street is the heart of this great town. Learn why this charming community is the greatest thing since ... well, you know.

Support Main Street

With support, we can bring new energy to the downtown and benefit the community in many different ways.

What's Happening?

October 31, 2018

November 24, 2018
Small Business Saturday

What's new?

Main Street Chillicothe welcomes Mad Toppers to our downtown Main Street family. The restaurant is owned by Mickey and Chrisi Criner. They have three daughters, Jaime, age 19 who attends c ...Read More
You asked and Main Street delivered by bringing back the MEMBERS ONLY -THE 80'S TRIBUTE BAND to entertain you. They are going to compliment our October 5, 2018 wine walk, by performing at o ...Read More
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2018 © Main Street Chillicothe  |  (660) 646-4071  |  514 Washington Street  |  Chillicothe, MO 64601