Main Street Chillicothe

Chillicothe is a thriving community in north central Missouri, and our historic Main Street is the heart of this great town. Learn why this charming community is the greatest thing since ... well, you know.

Support Main Street

With support, we can bring new energy to the downtown and benefit the community in many different ways.

What's Happening?

October 31st 2019
Chillicothe Boofest

What's new?

Are you as ready for spring and warm weather as I am? This happens to be my favorite time of the year downtown as the daffodils spring up in the permanent planters and flower pots are spread ...Read More
The Missouri Chapter of the American Planning Association (APA) presented three Great Places in Missouri awards on March 6th, 2019, at the State Capitol in Jefferson City, Missouri. The hon ...Read More
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2019 © Main Street Chillicothe  |  (660) 646-4071  |  514 Washington Street  |  Chillicothe, MO 64601