October 29, 2021

Main Street Chillicothe would like to invite you to participate in the twenty-second annual BooFest event scheduled for Friday,  October 29th, 2021. Details will be announced at a later time ... More >>

November 27th, 2021
Chillicothe, MO

Small Business Saturday is a way to recognize small and local businesses throughout the U.S. By supporting a small business, you’ll receive higher quality products, better customer service, ... More >>

October 8, 2021
Chillicothe, MO

Another great event is coming to downtown Main Street on October 8, 2021. This event is our annual October Wine Walk and Concert, featuring Member's Only. Since this event is a FUND R ... More >>

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